Endocrine Abstracts

Peptidyl growth hormone secretagogues (GHS), including ghrelin and growth hormone releasing peptides (GHRPs), have been reported to exert cardioprotective effects in experimental models of ischemia-reperfusion (I/R) injury through GH-independent pathway. Along this line, we have identified CD36 as a main target for GHRP binding and action in the heart. Yet, not much is known regarding the molecular mechanisms of the cardioprotective effects of GHRPs. The objective of this stud...